FDA Greenlights Testing ‘Ecstasy’ for PTSD Therapy
By Raymond March • Thursday December 14, 2017 10:04 AM PST •
MDMA, more commonly called “ecstasy” or “Molly,” is an illicit substance often taken to induce euphoria. The Controlled Substance Act considers MDMA a Schedule 1 controlled substance, which has no known medicinal benefits and a high likelihood of abuse.
Penalties for using or distributing MDMA are considerably high even for a Schedule 1 substance. In 2001, the U.S. federal government increased penalties for people convicted of dispensing over 50 grams of MDMA to a four-year prison sentence and up to $4 million in fines. These penalties could double if the buyer was harmed from the exchange. Similarly, possessing 5 grams of MDMA can result in a prison sentence ranging from 4 to 50 years.
Despite having no known medicinal benefits, the potential to cause harm, and higher-than-usual criminal penalties, the drug is enjoying new interest in psychotherapy research.
Currently, MDMA is in the early stages of FDA approval to treat post-traumatic stress disorder (PTSD). Furthermore, the FDA granted a “breakthrough therapy” status to MDMA last August. This means the agency will expedite testing of the drug. Breakthrough therapy status is granted only to drugs when “preliminary clinical evidence indicates that the drug may demonstrate substantial improvement [compared to other available treatments].”
Receiving treatment for PTSD in many cases requires patients to relive traumatic experiences to learn effective coping techniques. However, some memories and experiences are so distressing that patients cannot tolerate recalling them, making it difficult to complete therapy. MDMA, with its ability to produce euphoric feelings even when the brain perceives a threat, provides a unique ability to help those with PTSD.























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